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αConotoxin ArIB[V11L,V16D] is a potent and selective antagonist at rat and human native α7 nicotinic acetylcholine receptors

A recently developed α-conotoxin, α-CtxArIB[V11L,V16D] is a potent and selective competitive antagonist at rat recombinant α7 nicotinic acetylcholine receptors (nAChRs), making it an attractive probe for this receptor subtype. α7 nAChRs are potential therapeutic targets that are widely expressed in...

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Detalhes bibliográficos
Main Authors: Innocent, Neal, Livingstone, Phil D., Hone, Arik, Kimura, Atsuko, Young, Tracey, Whiteaker, Paul, McIntosh, J. Michael, Wonnacott, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596936/
https://ncbi.nlm.nih.gov/pubmed/18664588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.142943
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