αConotoxin ArIB[V11L,V16D] is a potent and selective antagonist at rat and human native α7 nicotinic acetylcholine receptors

A recently developed α-conotoxin, α-CtxArIB[V11L,V16D] is a potent and selective competitive antagonist at rat recombinant α7 nicotinic acetylcholine receptors (nAChRs), making it an attractive probe for this receptor subtype. α7 nAChRs are potential therapeutic targets that are widely expressed in...

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Bibliografiska uppgifter
Huvudupphovsmän: Innocent, Neal, Livingstone, Phil D., Hone, Arik, Kimura, Atsuko, Young, Tracey, Whiteaker, Paul, McIntosh, J. Michael, Wonnacott, Susan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596936/
https://ncbi.nlm.nih.gov/pubmed/18664588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.142943
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