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Folding mechanisms of individual β-hairpins in a Gō model of Pin1 WW domain by all-atom molecular dynamics simulations

This paper examines the folding mechanism of an individual β-hairpin in the presence of other hairpins by using an off-lattice model of a small triple-stranded antiparallel β-sheet protein, Pin1 WW domain. The turn zipper model and the hydrophobic collapse model originally developed for a single β-h...

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Autors principals: Luo, Zhonglin, Ding, Jiandong, Zhou, Yaoqi
Format: Artigo
Idioma:Inglês
Publicat: American Institute of Physics 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596927/
https://ncbi.nlm.nih.gov/pubmed/18554060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.2936832
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