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Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for presentation of transformed self

Protein phosphorylation generates a source of phosphopeptides that are presented by major histocompatibility complex (MHC) class I molecules and recognized by T cells. As deregulated phosphorylation is a hallmark of malignant transformation, the differential display of phosphorylated peptides on can...

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Detalhes bibliográficos
Main Authors: Mohammed, Fiyaz, Cobbold, Mark, Zarling, Angela L., Salim, Mahboob, Barrett-Wilt, Gregory A., Shabanowitz, Jeffrey, Hunt, Donald F., Engelhard, Victor H., Willcox, Benjamin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596764/
https://ncbi.nlm.nih.gov/pubmed/18836451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1660
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