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Fusion Antibody for Alzheimer’s Disease with Bi-Directional Transport Across the Blood-Brain Barrier and Abeta Fibril Disaggregation

Delivery of monoclonal antibody therapeutics across the blood-brain barrier is an obstacle to the diagnosis or therapy of CNS disease with antibody drugs. The immune therapy of Alzheimer’s disease attempts to disaggregate the amyloid plaque of Alzheimer’s disease with an anti-Abeta monoclonal antibo...

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Hlavní autoři: Boado, Ruben J., Zhang, Yufeng, Zhang, Yun, Xia, Chun-Fang, Pardridge, William M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596591/
https://ncbi.nlm.nih.gov/pubmed/17315944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc060349x
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