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Fusion Antibody for Alzheimer’s Disease with Bi-Directional Transport Across the Blood-Brain Barrier and Abeta Fibril Disaggregation

Delivery of monoclonal antibody therapeutics across the blood-brain barrier is an obstacle to the diagnosis or therapy of CNS disease with antibody drugs. The immune therapy of Alzheimer’s disease attempts to disaggregate the amyloid plaque of Alzheimer’s disease with an anti-Abeta monoclonal antibo...

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Detalhes bibliográficos
Main Authors: Boado, Ruben J., Zhang, Yufeng, Zhang, Yun, Xia, Chun-Fang, Pardridge, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596591/
https://ncbi.nlm.nih.gov/pubmed/17315944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc060349x
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