Extracellular Nampt Promotes Macrophage Survival via a Nonenzymatic Interleukin-6/STAT3 Signaling Mechanism

Macrophages play key roles in obesity-associated pathophysiology, including inflammation, atherosclerosis, and cancer, and processes that affect the survival-death balance of macrophages may have an important impact on obesity-related diseases. Adipocytes and other cells secrete a protein called ext...

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Hlavní autoři: Li, Yankun, Zhang, Yuan, Dorweiler, Bernhard, Cui, Dongying, Wang, Tao, Woo, Connie W., Brunkan, Cynthia S., Wolberger, Cynthia, Imai, Shin-ichiro, Tabas, Ira
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596403/
https://ncbi.nlm.nih.gov/pubmed/18945671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805866200
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