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Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways
During inflammation, a large amount of arachidonic acid (AA) is released into the cellular milieu and cyclooxygenase enzymes convert this AA to prostaglandins that in turn sensitize pain pathways. However, AA is also converted to natural epoxyeicosatrienoic acids (EETs) by cytochrome P450 enzymes. E...
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596245/ https://ncbi.nlm.nih.gov/pubmed/19028872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809765105 |
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