Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

Mammalian cells fuel their growth and proliferation through the catabolism of two main substrates: glucose and glutamine. Most of the remaining metabolites taken up by proliferating cells are not catabolized, but instead are used as building blocks during anabolic macromolecular synthesis. Investiga...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Wise, David R., DeBerardinis, Ralph J., Mancuso, Anthony, Sayed, Nabil, Zhang, Xiao-Yong, Pfeiffer, Harla K., Nissim, Ilana, Daikhin, Evgueni, Yudkoff, Marc, McMahon, Steven B., Thompson, Craig B.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596212/
https://ncbi.nlm.nih.gov/pubmed/19033189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810199105
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars