Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

Mammalian cells fuel their growth and proliferation through the catabolism of two main substrates: glucose and glutamine. Most of the remaining metabolites taken up by proliferating cells are not catabolized, but instead are used as building blocks during anabolic macromolecular synthesis. Investiga...

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Detaylı Bibliyografya
Asıl Yazarlar: Wise, David R., DeBerardinis, Ralph J., Mancuso, Anthony, Sayed, Nabil, Zhang, Xiao-Yong, Pfeiffer, Harla K., Nissim, Ilana, Daikhin, Evgueni, Yudkoff, Marc, McMahon, Steven B., Thompson, Craig B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596212/
https://ncbi.nlm.nih.gov/pubmed/19033189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810199105
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