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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
Mammalian cells fuel their growth and proliferation through the catabolism of two main substrates: glucose and glutamine. Most of the remaining metabolites taken up by proliferating cells are not catabolized, but instead are used as building blocks during anabolic macromolecular synthesis. Investiga...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596212/ https://ncbi.nlm.nih.gov/pubmed/19033189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810199105 |
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