Selective A(3) Adenosine Receptor Antagonists Derived from Nucleosides Containing a Bicyclo[3.1.0]hexane Ring System

We have prepared 5′-modified derivatives of adenosine and a corresponding (N)-methanocarba nucleoside series containing a bicyclo[3.1.0]hexane ring system in place of the ribose moiety. The compounds were examined in binding assays at three subtypes of adenosine receptors (ARs) and in functional ass...

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Main Authors: Melman, Artem, Wang, Ben, Joshi, Bhalchandra V., Gao, Zhan-Guo, de Castro, Sonia, Heller, Cara L., Kim, Soo-Kyung, Jeong, Lak Shin, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593936/
https://ncbi.nlm.nih.gov/pubmed/18752961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.08.007
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