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Notch signaling regulates growth and differentiation in the mammalian lens

The Notch signal transduction pathway regulates the decision to proliferate versus differentiate. Although there are a myriad of mouse models for the Notch pathway, surprisingly little is known about how these genes regulate early eye development, particularly in the anterior lens. We employed both...

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Autori principali: Rowan, Sheldon, Conley, Kevin W., Le, Tien T., Donner, Amy L., Maas, Richard L., Brown, Nadean L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593917/
https://ncbi.nlm.nih.gov/pubmed/18588871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.06.002
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