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The Pleckstrin Homology Domain of Phospholipase Cβ Transmits Enzymatic Activation through Modulation of Membrane - Domain Orientation
Phospholipase C-beta (PLCβ) enzymes are activated by Gαq and Gβγ subunits and catalyze the hydrolysis of the minor membrane lipid phosphatidylinositol 4,5 bisphosphate (PI(4,5)P(2)). Activation of PLCβ(2) by Gβγ subunits has been shown to be conferred through its N-terminal pleckstrin homology (PH)...
Kaydedildi:
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593903/ https://ncbi.nlm.nih.gov/pubmed/16669615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052317n |
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