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Stimulation of Phospholipase Cβ by Membrane Interactions, Interdomain Movmement, and G protein Binding - How Many Ways Can You Activate an Enzyme?
Signaling proteins are usually composed of one or more conserved structural domains. These domains are usually regulatory in nature by binding to specific activators or effectors, or species that regulate cellular location, etc. Inositol-specific mammalian phospholipase C (PLC) enzymes are multidoma...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1963342/ https://ncbi.nlm.nih.gov/pubmed/17524618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.04.006 |
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