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Stimulation of Phospholipase Cβ by Membrane Interactions, Interdomain Movmement, and G protein Binding - How Many Ways Can You Activate an Enzyme?

Signaling proteins are usually composed of one or more conserved structural domains. These domains are usually regulatory in nature by binding to specific activators or effectors, or species that regulate cellular location, etc. Inositol-specific mammalian phospholipase C (PLC) enzymes are multidoma...

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Bibliographic Details
Main Authors: DRIN, Guillaume, SCARLATA, Suzanne
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1963342/
https://ncbi.nlm.nih.gov/pubmed/17524618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2007.04.006
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