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Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges
Serotonin (5HT) is a powerful modulator of respiratory circuitry in vitro but its role in the development of breathing behavior in vivo is poorly understood. Here we show, using 5HT neuron-deficient Pet-1 (Pet-1(−/−)) neonates, that serotonergic function is required for the normal timing of postnata...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593840/ https://ncbi.nlm.nih.gov/pubmed/17656160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2007.06.002 |
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