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Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges

Serotonin (5HT) is a powerful modulator of respiratory circuitry in vitro but its role in the development of breathing behavior in vivo is poorly understood. Here we show, using 5HT neuron-deficient Pet-1 (Pet-1(−/−)) neonates, that serotonergic function is required for the normal timing of postnata...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Erickson, Jeffery T., Shafer, Geoffrey, Rossetti, Michael D., Wilson, Christopher G., Deneris, Evan S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593840/
https://ncbi.nlm.nih.gov/pubmed/17656160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2007.06.002
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