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Duplication of the IGFBP-2 Gene in Teleost Fish: Protein Structure and Functionality Conservation and Gene Expression Divergence
BACKGROUND: Insulin-like growth factor binding protein-2 (IGFBP-2) is a secreted protein that binds and regulates IGF actions in controlling growth, development, reproduction, and aging. Elevated expression of IGFBP-2 is often associated with progression of many types of cancers. METHODOLOGY/PRINCIP...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593780/ https://ncbi.nlm.nih.gov/pubmed/19081843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003926 |
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