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Duplication of the IGFBP-2 Gene in Teleost Fish: Protein Structure and Functionality Conservation and Gene Expression Divergence

BACKGROUND: Insulin-like growth factor binding protein-2 (IGFBP-2) is a secreted protein that binds and regulates IGF actions in controlling growth, development, reproduction, and aging. Elevated expression of IGFBP-2 is often associated with progression of many types of cancers. METHODOLOGY/PRINCIP...

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Detalhes bibliográficos
Main Authors: Zhou, Jianfeng, Li, Wenhong, Kamei, Hiroyasu, Duan, Cunming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593780/
https://ncbi.nlm.nih.gov/pubmed/19081843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003926
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