Distinct FAK-Src activation events promote α5β1 and α4β1 integrin-stimulated neuroblastoma cell motility

Signals from fibronectin-binding integrins promote neural crest cell motility during development in part through protein-tyrosine kinase (PTK) activation. Neuroblastoma (NB) is a neural crest malignancy with high metastatic potential. We find that α4 and α5 integrins are present in late-stage NB tum...

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Autori principali: Wu, Lihua, Bernard-Trifilo, Joie A., Lim, Yangmi, Lim, Ssang-Taek, Mitra, Satyajit K., Uryu, Sean, Chen, Min, Pallen, Catherine J., Cheung, Nai-Kong V., Mikolon, David, Mielgo, Ainhoa, Stupack, Dwayne G., Schlaepfer, David D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593630/
https://ncbi.nlm.nih.gov/pubmed/17828307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210770
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