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mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization
The Tuberous Sclerosis Complex component, TSC1, functions as a tumor suppressor via its regulation of diverse cellular processes, particularly cell growth. TSC1 exists in a complex with TSC2 and functions primarily as a key negative regulator of mammalian target of rapamycin complex 1 (mTORC1) signa...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593615/ https://ncbi.nlm.nih.gov/pubmed/19052232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810584105 |
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