Chromatin structure analyses identify miRNA promoters

Although microRNAs (miRNAs) are key regulators of gene expression in normal human physiology and disease, transcriptional regulation of miRNAs is poorly understood, because most miRNA promoters have not yet been characterized. We identified the proximal promoters of 175 human miRNAs by combining nuc...

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Autori principali: Ozsolak, Fatih, Poling, Laura L., Wang, Zhengxin, Liu, Hui, Liu, X. Shirley, Roeder, Robert G., Zhang, Xinmin, Song, Jun S., Fisher, David E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593607/
https://ncbi.nlm.nih.gov/pubmed/19056895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1706508
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