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Identifying and Mitigating Bias in Next-Generation Sequencing Methods for Chromatin Biology

Next generation sequencing (NGS) technologies have been used in diverse ways to investigate facets of chromatin biology by identifying genomic loci that are bound by transcription factors, occupied by nucleosomes, accessible to nuclease cleavage, or physically interact with remote genomic loci. Reac...

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Detalhes bibliográficos
Publicado no:Nat Rev Genet
Main Authors: Meyer, Clifford A., Liu, X. Shirley
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473780/
https://ncbi.nlm.nih.gov/pubmed/25223782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3788
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