Chromatin structure analyses identify miRNA promoters

Although microRNAs (miRNAs) are key regulators of gene expression in normal human physiology and disease, transcriptional regulation of miRNAs is poorly understood, because most miRNA promoters have not yet been characterized. We identified the proximal promoters of 175 human miRNAs by combining nuc...

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Autors principals: Ozsolak, Fatih, Poling, Laura L., Wang, Zhengxin, Liu, Hui, Liu, X. Shirley, Roeder, Robert G., Zhang, Xinmin, Song, Jun S., Fisher, David E.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593607/
https://ncbi.nlm.nih.gov/pubmed/19056895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1706508
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