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Cdc25A Serine 123 Phosphorylation Couples Centrosome Duplication with DNA Replication and Regulates Tumorigenesis

The cell division cycle 25A (Cdc25A) phosphatase is a critical regulator of cell cycle progression under normal conditions and after stress. Stress-induced degradation of Cdc25A has been proposed as a major way of delaying cell cycle progression. In vitro studies pointed toward serine 123 as a key s...

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Detalhes bibliográficos
Main Authors: Shreeram, Sathyavageeswaran, Hee, Weng Kee, Bulavin, Dmitry V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593435/
https://ncbi.nlm.nih.gov/pubmed/18936171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00138-08
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