DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6

Centrosome number is tightly controlled during the cell cycle to ensure proper spindle assembly and cell division. However, the underlying mechanism that controls centrosome number remains largely unclear. We show herein that the DNA replication licensing factor Cdc6 is recruited to the proximal sid...

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Publicado en:Nat Commun
Autores principales: Xu, Xiaowei, Huang, Shijiao, Zhang, Boyan, Huang, Fan, Chi, Wangfei, Fu, Jingyan, Wang, Gang, Li, Si, Jiang, Qing, Zhang, Chuanmao
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414174/
https://ncbi.nlm.nih.gov/pubmed/28447620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15164
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