Licensing of Yeast Centrosome Duplication Requires Phosphoregulation of Sfi1

Duplication of centrosomes once per cell cycle is essential for bipolar spindle formation and genome maintenance and is controlled in part by cyclin-dependent kinases (Cdks). Our study identifies Sfi1, a conserved component of centrosomes, as the first Cdk substrate required to restrict centrosome d...

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Main Authors: Avena, Jennifer S., Burns, Shannon, Yu, Zulin, Ebmeier, Christopher C., Old, William M., Jaspersen, Sue L., Winey, Mark
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207612/
https://ncbi.nlm.nih.gov/pubmed/25340401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004666
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