Glycosylation of gp41 of Simian Immunodeficiency Virus Shields Epitopes That Can Be Targets for Neutralizing Antibodies

Human immunodeficiency virus type 1 and simian immunodeficiency virus possess three closely spaced, highly conserved sites for N-linked carbohydrate attachment in the extracellular domain of the transmembrane protein gp41. We infected rhesus monkeys with a variant of cloned SIVmac239 lacking the sec...

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Bibliographische Detailangaben
Hauptverfasser: Yuste, Eloìsa, Bixby, Jacqueline, Lifson, Jeffrey, Sato, Shuji, Johnson, Welkin, Desrosiers, Ronald
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593353/
https://ncbi.nlm.nih.gov/pubmed/18829751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01382-08
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