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The 'zinc knuckle' motif of Early B cell Factor is required for transcriptional activation of B cell-specific genes
Early B cell factor (EBF) is a critical regulator of B lymphocyte-specific gene transcription. EBF functions, in part, by binding to regulatory sites of genes required for the pre-B- and mature B cell receptors. These DNA targets include the promoters of the mb-1 and Vpreb1 genes that encode Ig-α an...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593158/ https://ncbi.nlm.nih.gov/pubmed/18606452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.05.018 |
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