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Polymeric nanogels containing the triphosphate form of cytotoxic nucleoside analogues show antitumor activity against breast and colorectal cancer cell lines
BACKGROUND: The therapeutic efficiency of anticancer NA strongly depends on their intracellular accumulation and conversion into 5’-triphosphates. Since active NATP cannot be directly administrated due to instability, we present here a strategy of nanoencapsulation of these active drugs for efficien...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593126/ https://ncbi.nlm.nih.gov/pubmed/18852140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0616 |
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