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Crosslinked Polymeric Nanogel Formulations of 5′-Triphosphates of Nucleoside Analogs: Role of the Cellular Membrane in Drug Release

Activation of cytotoxic nucleoside analogs in vivo depends primarily on their cell-specific phosphorylation. Anticancer chemotherapy using nucleoside analogs may be significantly enhanced by intracellular administration of active phosphorylated drugs. However, the cellular transport of anionic compo...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Vinogradov, Serguei V., Kohli, Ekta, Zeman, Arin D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351166/
https://ncbi.nlm.nih.gov/pubmed/16323952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp0500364
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