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Crosslinked Polymeric Nanogel Formulations of 5′-Triphosphates of Nucleoside Analogs: Role of the Cellular Membrane in Drug Release
Activation of cytotoxic nucleoside analogs in vivo depends primarily on their cell-specific phosphorylation. Anticancer chemotherapy using nucleoside analogs may be significantly enhanced by intracellular administration of active phosphorylated drugs. However, the cellular transport of anionic compo...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1351166/ https://ncbi.nlm.nih.gov/pubmed/16323952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp0500364 |
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