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Biotinyl-methyl 4-(amidomethyl) benzoate is a competitive inhibitor of human biotinidase

Posttranslational modification of histones by biotinylation can be catalyzed by both biotinidase (BTD) and holocarboxylase synthetase (HCS). Biotinylation of histones is an important epigenetic mechanism to regulate gene expression, DNA repair, and chromatin remodeling. The role of BTD in histone bi...

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Detalhes bibliográficos
Main Authors: Kobza, Keyna A., Chaiseeda, Kittichai, Sarath, Gautam, Takacs, James M., Zempleni, Janos
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593093/
https://ncbi.nlm.nih.gov/pubmed/18479898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2007.11.002
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