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Biotinyl-methyl 4-(amidomethyl) benzoate is a competitive inhibitor of human biotinidase
Posttranslational modification of histones by biotinylation can be catalyzed by both biotinidase (BTD) and holocarboxylase synthetase (HCS). Biotinylation of histones is an important epigenetic mechanism to regulate gene expression, DNA repair, and chromatin remodeling. The role of BTD in histone bi...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593093/ https://ncbi.nlm.nih.gov/pubmed/18479898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2007.11.002 |
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