In Vitro Activities at pH 5.0 and pH 7.0 and In Vivo Efficacy of Flucytosine against Aspergillus fumigatus

The antifungal agent flucytosine was found to be active in vitro against Aspergillus fumigatus isolates when the MIC was determined at pH 5.0 instead of pH 7.0. The in vitro MIC at pH 5.0 corresponded to the in vivo efficacy of flucytosine monotherapy in a murine model of invasive aspergillosis.

Na minha lista:
Detalhes bibliográficos
Main Authors: Verweij, Paul E., Te Dorsthorst, Debbie T. A., Janssen, Willem H. P., Meis, Jacques F. G. M., Mouton, Johan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592878/
https://ncbi.nlm.nih.gov/pubmed/18794382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00491-08
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados