Pharmacokinetics of l-Arginine in Adults with Moderately Severe Malaria

Severe malaria is associated with decreased nitric oxide (NO) production and low plasma concentrations of l-arginine, the substrate for NO synthase. Supplementation with l-arginine has the potential to improve NO bioavailability and outcomes. We developed a pharmacokinetic model for l-arginine in mo...

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Hlavní autoři: Yeo, Tsin W., Rooslamiati, Indri, Gitawati, Retno, Tjitra, Emiliana, Lampah, Daniel A., Kenangalem, Enny, McNeil, Yvette R., Price, Richard N., Anstey, Nicholas M., Duffull, Stephen B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592856/
https://ncbi.nlm.nih.gov/pubmed/18838585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00421-08
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