A Randomized Pilot Study of L-Arginine Infusion in Severe Falciparum Malaria: Preliminary Safety, Efficacy and Pharmacokinetics

BACKGROUND: Decreased nitric oxide (NO) and hypoargininemia are associated with severe falciparum malaria and may contribute to severe disease. Intravenous L-arginine increases endothelial NO in moderately-severe malaria (MSM) without adverse effects. The safety, efficacy and pharmacokinetics of L-a...

Full description

Saved in:
Bibliographic Details
Main Authors: Yeo, Tsin W., Lampah, Daniel A., Rooslamiati, Indri, Gitawati, Retno, Tjitra, Emiliana, Kenangalem, Enny, Price, Ric N., Duffull, Stephen B., Anstey, Nicholas M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726665/
https://ncbi.nlm.nih.gov/pubmed/23922746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069587
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items