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Amyloid-β peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A(2)

Oligomeric amyloid-β peptide (Aβ) is known to induce cytotoxic effects and to damage cell functions in Alzheimer’s disease. However, mechanisms underlying the effects of Aβ on cell membranes have yet to be fully elucidated. In this study, Aβ 1–42 (Aβ(42)) was shown to cause a temporal biphasic chang...

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Detalhes bibliográficos
Main Authors: Hicks, Jacob B., Lai, Yinzhi, Sheng, Wenwen, Yang, Xiaoguang, Zhu, Donghui, Sun, Grace Y., Lee, James C-M
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592609/
https://ncbi.nlm.nih.gov/pubmed/18725190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2008.07.027
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