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Phospholipases A(2) Mediate Amyloid-β Peptide-Induced Mitochondrial Dysfunction

Mitochondrial dysfunction has been implicated in the pathophysiology of Alzheimer's disease (AD) brains. To unravel the mechanism(s) underlying this dysfunction, we demonstrate that phospholipases A(2) (PLA(2)s), namely the cytosolic and the calcium-independent PLA(2)s (cPLA(2) and iPLA(2)), ar...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhu, Donghui, Lai, Yinzhi, Shelat, Phullara B., Hu, Chunhua, Sun, Grace Y., Lee, James C-M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674660/
https://ncbi.nlm.nih.gov/pubmed/17065451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3505-06.2006
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