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Leptin treatment prevents type I diabetic marrow adiposity but not bone loss in mice
Leptin is a hormone secreted by adipocytes that is implicated in the regulation of bone density. Serum leptin levels are decreased in rodent models of type 1 (T1-) diabetes and in diabetic patients. Whether leptin mediates diabetic bone changes is unclear. Therefore, we treated control and T1-diabet...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592498/ https://ncbi.nlm.nih.gov/pubmed/18932203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21608 |
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