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Leptin treatment prevents type I diabetic marrow adiposity but not bone loss in mice

Leptin is a hormone secreted by adipocytes that is implicated in the regulation of bone density. Serum leptin levels are decreased in rodent models of type 1 (T1-) diabetes and in diabetic patients. Whether leptin mediates diabetic bone changes is unclear. Therefore, we treated control and T1-diabet...

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Bibliographic Details
Main Authors: Motyl, Katherine J., McCabe, Laura R.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592498/
https://ncbi.nlm.nih.gov/pubmed/18932203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21608
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