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Factor VIIa binding to endothelial cell protein C receptor

Recent studies have shown that factor VIIa (FVIIa) binds specifically to endothelial protein C receptor (EPCR), a known cellular receptor for protein C and activated protein C, on the endothelium. The formation of FVIIa:EPCR complexes neither supports the activation of coagulation nor modulates tiss...

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Détails bibliographiques
Auteurs principaux: Rao, L. Vijaya Mohan, Pendurthi, Usha R.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2591929/
https://ncbi.nlm.nih.gov/pubmed/18691496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0049-3848(08)70009-4
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