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Spatio-temporal Regulation of Ras Activity Provides Directional Sensing

Cells' ability to detect and orient themselves in chemoattractant gradients has been the subject of numerous studies, but the underlying molecular mechanisms remain largely unknown [1]. Ras activation is the earliest polarized response to chemoattractant gradients downstream from heterotrimeric...

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Autors principals: Zhang, Sheng, Charest, Pascale G., Firtel, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590931/
https://ncbi.nlm.nih.gov/pubmed/18948008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.08.069
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