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Characterization of the steric defense of the HIV-1 gp41 N-trimer region
During viral entry, HIV gp41 adopts a transient conformation called the “prehairpin intermediate” in which a highly conserved therapeutic target, the N-trimer, is exposed. Despite extensive discovery efforts, potent and broadly neutralizing antibodies that target the N-trimer are elusive. We previou...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2590922/ https://ncbi.nlm.nih.gov/pubmed/18802030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.038273.108 |
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