Novel fold of VirA, a type III secretion system effector protein from Shigella flexneri

VirA, a secreted effector protein from Shigella sp., has been shown to be necessary for its virulence. It was also reported that VirA might be related to papain-like cysteine proteases and cleave α-tubulin, thus facilitating intracellular spreading. We have now determined the crystal structure of Vi...

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Hlavní autoři: Davis, Jamaine, Wang, Jiawei, Tropea, Joseph E., Zhang, Di, Dauter, Zbigniew, Waugh, David S., Wlodawer, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
Protein Structure Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590913/
https://ncbi.nlm.nih.gov/pubmed/18787201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.037978.108
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