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Escape of Actively Secreting Shigella flexneri from ATG8/LC3-Positive Vacuoles Formed during Cell-To-Cell Spread Is Facilitated by IcsB and VirA

The enteropathogenic bacterium Shigella flexneri uses a type 3 secretion apparatus (T3SA) to transfer proteins dubbed translocators and effectors inside host cells, inducing bacterial uptake and subsequent lysis of the entry vacuole. Once in the cytoplasm, the outer membrane protein IcsA induces act...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Campbell-Valois, François-Xavier, Sachse, Martin, Sansonetti, Philippe J., Parsot, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447254/
https://ncbi.nlm.nih.gov/pubmed/26015503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02567-14
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