Caricamento...

Recombinant Collagen Studies Link the Severe Conformational Changes Induced by Osteogenesis Imperfecta Mutations to the Disruption of a Set of Interchain Salt Bridges

The clinical severity of Osteogenesis Imperfecta (OI), also known as the brittle bone disease, relates to the extent of conformational changes in the collagen triple helix induced by Gly substitution mutations. The lingering question is why Gly substitutions at different locations of collagen cause...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Xu, Ke, Nowak, Iwona, Kirchner, Michele, Xu, Yujia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590706/
https://ncbi.nlm.nih.gov/pubmed/18845533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805485200
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !