Effect of Leucine to Phenylalanine Substitution on the Nonpolar Face of a Class A Amphipathic Helical Peptide on Its Interaction with Lipid: HIGH RESOLUTION SOLUTION NMR STUDIES OF 4F-DIMYRISTOYLPHOSPHATIDYLCHOLINE DISCOIDAL COMPLEX

Model class A amphipathic helical peptides mimic several properties of apolipoprotein A-I (apoA-I), the major protein component of high density lipoproteins. Previously, we reported the NMR structures of Ac-18A-NH(2) (renamed as 2F because of two phenylalanines), the base-line model class A amphipat...

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Detalhes bibliográficos
Main Authors: Mishra, Vinod K., Palgunachari, Mayakonda N., Krishna, N. Rama, Glushka, John, Segrest, Jere P., Anantharamaiah, G. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590695/
https://ncbi.nlm.nih.gov/pubmed/18845546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806384200
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