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Perinatal Loss of Nkx2-5 Results in Rapid Conduction and Contraction Defects
Homeobox transcription factor Nkx2-5, highly expressed in heart, is a critical factor during early embryonic cardiac development. In this study, using tamoxifen-inducible Nkx2-5 knockout mice, we demonstrate the role of Nkx2-5 in conduction and contraction in neonates within 4 days after perinatal t...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2590500/ https://ncbi.nlm.nih.gov/pubmed/18689573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.171835 |
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