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Effect of carrier priming on immunogenicity of saccharide-protein conjugate vaccines.

Previous studies with saccharide-protein conjugates have demonstrated that antibody responses to the saccharide can be improved by the preexistence of carrier immunity. Here we report that prior exposure to the carrier protein can either enhance or suppress antibody response to polysaccharides admin...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Peeters, C C, Tenbergen-Meekes, A M, Poolman, J T, Beurret, M, Zegers, B J, Rijkers, G T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258913/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1894357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.10.3504-3510.1991
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