Effect of carrier priming on immunogenicity of saccharide-protein conjugate vaccines.

Previous studies with saccharide-protein conjugates have demonstrated that antibody responses to the saccharide can be improved by the preexistence of carrier immunity. Here we report that prior exposure to the carrier protein can either enhance or suppress antibody response to polysaccharides admin...

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Pubblicato in:	Infect Immun
Autori principali:	Peeters, C C, Tenbergen-Meekes, A M, Poolman, J T, Beurret, M, Zegers, B J, Rijkers, G T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1894357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.10.3504-3510.1991
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