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Effect of carrier priming on immunogenicity of saccharide-protein conjugate vaccines.

Previous studies with saccharide-protein conjugates have demonstrated that antibody responses to the saccharide can be improved by the preexistence of carrier immunity. Here we report that prior exposure to the carrier protein can either enhance or suppress antibody response to polysaccharides admin...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Peeters, C C, Tenbergen-Meekes, A M, Poolman, J T, Beurret, M, Zegers, B J, Rijkers, G T
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258913/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1894357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.10.3504-3510.1991
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